Paired box 8
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. The PAX gene family has an important role in the formation of tissues and organs during … See more Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene. See more • Pax genes See more • PAX8+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • "Xenbase Gene: Summary for pax8, species: Xenopus tropicalis" See more The PAX8 gene is also associated congenital hypothyroidism due to thyroid dysgenesis because of its role in growth and development of the thyroid gland. A mutation in the PAX8 gene could prevent or disrupt normal development. These mutations can … See more • Poleev A, Fickenscher H, Mundlos S, Winterpacht A, Zabel B, Fidler A, Gruss P, Plachov D (November 1992). "PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors". Development. 116 (3): 611–23. See more Web1/100. Primary antibody incubation for 30 minutes at 4°C. IHC-P. 1/100. Perform heat mediated antigen retrieval with EDTA buffer pH 8.0 before commencing with IHC staining protocol. Primary antibody incubation for 10 minutes at room temperature. WB. 1/100. Predicted molecular weight: 48 kDa.
Paired box 8
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WebMay 1, 2009 · PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors. Poleev A et al: 14531904: 2003: Possible regulation of Wilms' tumour gene 1 (WT1) expression by the paired box genes PAX2 and PAX8 and by the haematopoietic transcription factor GATA-1 in human acute myeloid leukaemias. WebJun 7, 2024 · Qiu, P., Jie, Y., Ma, C. et al. Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with …
WebAug 16, 2024 · The association between epithelial cancers and paired-box gene 8 (PAX8) has been studied significantly before. PAX8 belongs to the paired-box gene family, which … WebPredicted to be located in nucleus. Is expressed in several structures, including endocrine system; mesoderm; nervous system; neurogenic field; and pronephros. Human ortholog (s) of this gene implicated in congenital hypothyroidism and congenital nongoitrous hypothyroidism 2. Orthologous to human PAX8 (paired box 8).
WebMar 20, 2024 · I have a set of paired data, and I'm using ggplot2.boxplot (of the easyGgplot2 package) with added (jittered) ... I'll likely go with nonjittered, but thanks for sharing both versions (although black boxes … WebPaired box 8 Recommended Applications Product Description Monoclonal Antibody against Human PAX8 Alternative Gene Names - Open Datasheet. Price. $505.00. Product Number. AMAb91488. Unit Size. Concentration. Lot dependent. Availability >10 in Stock. Ships. Ready to Ship. Share by E-mail Add to ...
WebMutations in the paired domain transcription factor PAX8 are a rare cause of congenital hypothyroidism due to thyroid dysgenesis [1]. Our findings suggest that PAX8 / PPAR gamma occurs frequently in follicular thyroid carcinomas, and the presence of this rearrangement is likely to prove highly suggestive of a malignant tumor [2].
WebPR:000012320 paired box protein Pax-8 (term hierarchy) InterPro Domains. IPR009057 Homeobox-like domain superfamily. IPR022130 Paired-box protein 2 C-terminal. … uk wings of fire coversWebJul 18, 2024 · Paired box 8 (PAX8) has been documented to be downregulated in gastric cancer. However, its biological function in this malignancy is poorly understood. In the … uk winner blows 10 millionWebpaired box gene 8; paired box protein Pax-8; paired domain gene 8; Description The PAX8 gene product is a member of the paired box (PAX) family of transcription factors. It is a transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such ... thompson tee discountWebOct 26, 2024 · 1 of 9 members of paired box gene (PAX) family of transcription factors that regulate organogenesis (Am J Surg Pathol 2011;35:1473) Involved in development of the central nervous system, … ukwins compsWebThis paired-box transcription factor exerts multiple actions during cortical development via regulating gene expression in progenitor cells, where its precise effects are heavily context-dependent (Manuel, Mi, Mason, & Price, 2015; Mi et al., 2013 ). For example, it regulates cell cycle length and exit in a cell-autonomous manner, but in such a ... uk winners eurovision song contestWebMcKnight, Cohen, Siddiqui: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." in: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) . Chia ... uk winning lotteryWebJun 5, 2024 · Background: The transcription factor paired box 8 (PAX8) was associated with type 2 congenital non-goitrous hypothyroidism (CHNG2), a clinical phenotype of congenital hypothyroidism (CH). Though studied in a few regions with different ethnicities, the incidence of PAX8 mutations varied, even among Chinese cohorts in different regions. … thompson technologies maternity leave